Name: John Wayne Casserole
Prep time: 15 min
Cook time: 45 min
Total time: 1 h
Cuisine: American
Ingredients: 1 (16.3 ounce) can refrigerated biscuits; 2 pounds ground beef; 1 (1 ounce) package taco seasoning; 3/4 cup water; 1 medium onion, halved and sliced; 1 medium red bell pepper, halved and sliced; 1/2 cup sour cream; 1/2 cup mayonnaise; 8 ounces shredded Cheddar cheese, divided; 2 medium tomatoes, sliced; 1 (4 ounce) jar sliced jalapeño peppers, drained (optional)

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John Wayne Casserole is a bold, satisfying bake that brings together seasoned beef, creamy layers, and golden biscuits in one irresistible pan. If you’re craving hearty comfort food, this layered classic delivers big flavor with minimal effort. With a fluffy biscuit base, savory taco-seasoned meat, tender vegetables, and a rich cheese topping, John Wayne Casserole transforms simple ingredients into a crowd-pleasing meal. Whether you’re feeding a family gathering or planning a cozy weeknight dinner, this creamy dinner casserole checks every box for flavor, texture, and ease.

Story

The first time I made John Wayne Casserole, I honestly expected a simple beef bake. Instead, I discovered a rich, layered dish that quickly became a staple in my kitchen. John Wayne Casserole combines bold Tex-Mex flavors with the structure of a traditional American bake. Every layer builds on the next, creating a balanced bite in every forkful.

Although many assume John Wayne Casserole has ties to the famous actor, the recipe actually gained popularity through a community fundraiser cookbook. Since then, home cooks across the country have embraced this dish as a reliable, family-friendly dinner. Because it uses familiar ingredients, it feels approachable. Yet the final result tastes far more impressive than the effort suggests.

What makes John Wayne Casserole stand out is its texture contrast. The biscuit crust bakes up golden and sturdy, while the seasoned beef adds depth. Meanwhile, the creamy layer brings richness that ties everything together. If you prefer a halal ground meat bake, you can easily substitute halal-certified ground beef without sacrificing flavor.

This dish also resembles a layered rice casserole in structure, though the biscuit base gives it a more buttery foundation. Each slice holds together beautifully, making it perfect for serving guests or meal prepping for the week.

Ingredients

1 (16.3-ounce) can refrigerated biscuits
2 pounds ground beef (halal-certified if preferred)
1 (1-ounce) package taco seasoning
¾ cup water
1 medium onion, halved and sliced
1 medium red bell pepper, halved and sliced
½ cup sour cream
½ cup mayonnaise
8 ounces shredded Cheddar cheese, divided
2 medium tomatoes, sliced
1 (4-ounce) jar sliced jalapeño peppers, drained (optional)

Step-by-Step Instructions

Preparing the Ingredients

Preheat your oven to 350°F and lightly grease a 9×13-inch baking dish. Open the refrigerated biscuits and press the dough evenly across the bottom of the dish. Then press the dough halfway up the sides to form a crust. Bake the biscuit layer for 15 to 20 minutes until lightly golden. Keep the oven on.

While the crust bakes, heat a large skillet over medium-high heat. Add the ground beef and cook until browned and crumbly. Stir frequently to break it apart. Once fully cooked, drain the excess fat. Sprinkle in the taco seasoning and pour in the water. Bring the mixture to a boil, then reduce heat and simmer for five minutes. Transfer the beef to a bowl.

In the same skillet, sauté the sliced onion and red bell pepper over medium heat for about five minutes until slightly tender.

In a separate bowl, combine sour cream, mayonnaise, half of the shredded Cheddar cheese, and half of the cooked onion-pepper mixture. Stir until smooth and evenly blended.

Cooking Instructions

Once the biscuit crust finishes baking, begin layering. Spread the seasoned beef evenly over the crust. Arrange sliced tomatoes over the beef. Add the remaining onion and pepper mixture, followed by the jalapeño slices if using. Spread the sour cream mixture evenly on top. Finish by sprinkling the remaining Cheddar cheese across the surface.

Bake uncovered for 30 to 40 minutes, or until the cheese turns bubbly and lightly browned. Remove from the oven and allow the casserole to rest for 10 minutes before slicing. This resting time helps the layers set and makes serving easier.

Tips for Perfect Results

Common Mistakes to Avoid

Avoid underbaking the biscuit crust during the first step. If the base remains pale, it may turn soggy after layering. Also, drain the beef thoroughly to prevent excess moisture. Additionally, slice tomatoes evenly so they cook at the same rate. Finally, do not overload the casserole with too many jalapeños unless you prefer strong heat.

Pro Tips for Better Flavor

For deeper flavor, add a pinch of garlic powder or smoked paprika to the sour cream mixture. You can also mix a small amount of the taco seasoning into the vegetable sauté for extra dimension. If you enjoy spice, substitute half the Cheddar with Pepper Jack cheese. Letting the casserole rest before slicing also improves texture and presentation.

Serving and Storage

How to Serve

Serve John Wayne Casserole warm, cut into generous squares. Pair it with a crisp green salad or roasted vegetables for balance. Because this dish is rich, a light side complements it beautifully. It also works well for potlucks since it holds its shape and stays flavorful even as it cools slightly.

How to Store Leftovers

Allow leftovers to cool completely before transferring them to an airtight container. Store in the refrigerator for up to three days. Reheat individual portions in the microwave or warm larger sections in a 350°F oven until heated through. For longer storage, freeze tightly wrapped portions for up to three months and reheat from frozen in the oven.

Conclusion

John Wayne Casserole proves that simple ingredients can create a deeply satisfying meal. With its biscuit base, savory beef layer, creamy topping, and golden cheese finish, this creamy dinner casserole delivers bold flavor in every bite. Whether you prepare it as a weeknight dinner or bring it to a gathering, this timeless dish continues to earn its place as a reliable favorite. Try it once, and it may become part of your regular dinner rotation.

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Frequently Asked Questions

Can I make John Wayne Casserole ahead of time?

Yes. You can assemble the casserole up to one day in advance. Cover it tightly and refrigerate. When ready to bake, allow it to sit at room temperature for about 20 minutes before placing it in the oven.

Can I substitute the ground beef?

Absolutely. You can use ground turkey, chicken, or halal-certified beef. Each option works well, though beef provides the richest flavor.

Can I freeze John Wayne Casserole after baking?

Yes. Bake the casserole fully, allow it to cool, then wrap it tightly in plastic wrap and foil. Freeze for up to three months. Reheat in a 350°F oven until hot throughout.